化工社化工社 化学情報印刷レポート · 研究参考用
1-Methyl-2-piperidinemethanol → N-methyl-2-piperidylmethyl N,N-dimethylaminoacetate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-Methyl-2-piperidinemethanol | HCID 89394 | — |
| 反応物 | Glycine, N,N-dimethyl-, ethyl ester | HCID 118412 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | N-methyl-2-piperidylmethyl N,N-dimethylaminoacetate | HCID 19753089 | — |
反応手順
A mixture of 75 g of ethyl N,N-dimethylglycinate, 75 g of 1-methyl-2-piperidylmethanol and 1 g of titanium tetra(n-butoxide) was heated at 45° C. until the amount of ethanol collected indicated the reaction was complete. After cooling a small amount of water was added, the mixture was filtered, and the filtrate was distilled under reduced pressure to provide N-methyl-2-piperidylmethyl N,N-dimethylaminoacetate.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05225513 |
| 出典データセット | uspto-grants-1993_07 |
| ORD ID | ord-d6308de8a1ec43cdb67084bf42d56e20 |
| 出典メモ | uspto-grants-1993_07 |