反应详情

A mixture of 75 g of ethyl N,N-dimethylglycinate, 75 g of 1-methyl-2-piperidylmethanol and 1 g of titanium tetra(n-butoxide) was heated at 45° C. until the amount of ethanol collected indicated the reaction was complete. After cooling a small amount of water was added, the mixture was filtered, and the filtrate was distilled under reduced pressure to provide N-methyl-2-piperidylmethyl N,N-dimethylaminoacetate.

1. customcollected
2. temperatureAfter cooling a small amount of water
3. additionwas added
4. filtrationthe mixture was filtered
5. distillationthe filtrate was distilled under reduced pressure