2-Chloro-4-nitropyridine 1-oxide → Pyridine, 2-chloro-4-methoxy-, 1-oxide

HRID 483758

反応式

HRID 483758 の反応式
[Na].[CH3:2][O-:3].[Na+].[Cl:5][C:6]1[CH:11]=[C:10]([N+]([O-])=O)[CH:9]=[CH:8][N+:7]=1[O-:15]>CO>[Cl:5][C:6]1[CH:11]=[C:10]([O:3][CH3:2])[CH:9]=[CH:8][N+:7]=1[O-:15]

参加物

5

反応物 3

HCID 844332-Chloro-4-nitropyridine 1-oxideHCID 5360545SodiumHCID 10942334Sodium Methoxide

生成物 1

HCID 15593755Pyridine, 2-chloro-4-methoxy-, 1-oxide

試薬・触媒・溶媒 1

HCID 887Methanol溶媒2 回

実験手順

Sodium (0.46 g) is dissolved in absolute methanol (50 ml) and the resultant solution of sodium methoxide is added to a solution of 2-chloro-4-nitropyridine-1-oxide (3.5 g, prepared as described in Example 1) in methanol (10 ml). The reaction mixture is allowed to stand at room temperature for 50 hours and is then subjected to rotary evaporation to give 2-chloro-4-methoxypyridine-1-oxide.

後処理

  1. customis then subjected to rotary evaporation

出典と根拠

ORDレコード
ord-20eeab3c45f14020a6979e4c216e0572
出典データセット
uspto-grants-1993_07
特許番号
USRE034313

関連ノート

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