2,5-Dichlorophenol → 2,5-Dichlorophenyl Dimethyloctylsilyl Ether

HRID 483867

反応式

HRID 483867 の反応式
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([Cl:8])=[CH:4][C:3]=1[OH:9].N1C=CN=C1.Cl[Si:16]([CH3:26])([CH3:25])[CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH3:24]>CN(C)C=O.[Cl-].[Na+]>[CH3:25][Si:16]([O:9][C:3]1[CH:4]=[C:5]([Cl:8])[CH:6]=[CH:7][C:2]=1[Cl:1])([CH3:26])[CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH3:24]

参加物

6

反応物 3

HCID 662,5-DichlorophenolHCID 795ImidazoleHCID 87482Chlorodimethyloctylsilane

生成物 1

HCID 539888402,5-Dichlorophenyl Dimethyloctylsilyl Ether

試薬・触媒・溶媒 2

HCID 5234Sodium Chloride溶媒HCID 6228Dimethylformamide溶媒

実験手順

To a solution of 3.75 g (0.023 mole) 2,5-dichlorophenol in 30 ml N,N-dimethylformamide are added 5.58 g (0.082 mole) imidazole and 16.6 ml (0.070 mole) chlorodimethyloctyl silane under argon. After stirring at room temperature for two hours, the mixture is diluted with an aqueous saturated sodium chloride solution and extracted with ether. The combined organic extracts are dried and condensed. The product is purified by column chromatography.

後処理

  1. extractionextracted with ether
  2. customThe combined organic extracts are dried
  3. customcondensed
  4. customThe product is purified by column chromatography

出典と根拠

ORDレコード
ord-3d90883c40d24a52b08099e78da52c02
出典データセット
uspto-grants-1993_07
特許番号
US05227457

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