反応式
Cl[C:2]1[CH:9]=[CH:8][C:5]([CH:6]=[O:7])=[C:4]([F:10])[CH:3]=1.ClC1C=C([F:20])C=CC=1C=O.S1(CCCC1)(=O)=O.[F-].[K+]>>[F:10][C:4]1[CH:3]=[C:2]([F:20])[CH:9]=[CH:8][C:5]=1[CH:6]=[O:7]参加物
5
実験手順
158.5 g (1 mol) of a mixture of 56% of 4-chloro-2-fluoro-benzaldehyde and 44% of 2-chloro-4-fluorobenzaldehyde were heated together with 700 g of sulfolane and 75 g (1.29 mol) of potassium fluoride at 215° C. for 10 h. The working up was carried out as in Example 1. 99.5 g of 2,4-difluorobenzaldehyde equivalent to 70% of the feed-stock was obtained.
出典と根拠
- ORDレコード
- ord-6c1a97fab7104349a0387170691bc375
- 出典データセット
- uspto-grants-1993_07
- 特許番号
- US05227531
関連ノート
読み込み中…