Acetic Anhydride → HCID 14543798、化合物
反応式
[C:1]([O:4][CH:5]1[NH:8][C:7](=[O:9])[CH:6]1[CH2:10][CH2:11][CH3:12])(=[O:3])[CH3:2].[C:13](OC(=O)C)(=[O:15])[CH3:14]>N1C=CC=CC=1>[C:13]([N:8]1[CH:5]([O:4][C:1](=[O:3])[CH3:2])[CH:6]([CH2:10][CH2:11][CH3:12])[C:7]1=[O:9])(=[O:15])[CH3:14]参加物
4
実験手順
A mixture of 56 mg (0.33 mM) 4-acetoxy-3-propylazetidin-2-one, 1 ml acetic anhydride and 1 ml pyridine was stirred at 100° in a sealed tube for 24 hours. After concentrating in vacuo the residue was chromatographed on silica gel in hexane/ethyl acetate, to yield 16 mg (23%) 1-acetyl-4-acetoxy-3-n-propyl-azetidine-2-one.
後処理
- concentrationAfter concentrating in vacuo the residue
- customwas chromatographed on silica gel in hexane/ethyl acetate
出典と根拠
- ORDレコード
- ord-00940632717b4d1bb5e2ac002a7f903a
- 出典データセット
- uspto-grants-1993_07
- 特許番号
- US05229381
反応ノート
読み込み中…