2-Aminoindane → 6-(2-Indanylamino)purine

HRID 48446

反応式

HRID 48446 の反応式
Cl[C:2]1[N:10]=[CH:9][N:8]=[C:7]2[C:3]=1[NH:4][CH:5]=[N:6]2.[NH2:11][CH:12]1[CH2:20][C:19]2[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=2)[CH2:13]1>C(O)C>[CH2:13]1[C:14]2[C:19](=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH2:20][CH:12]1[NH:11][C:2]1[N:10]=[CH:9][N:8]=[C:7]2[C:3]=1[NH:4][CH:5]=[N:6]2

参加物

4

反応物 2

HCID 763102-AminoindaneHCID 53592776-Chloropurine

生成物 1

HCID 227195886-(2-Indanylamino)purine収率 40%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

Using 6-chloropurine (150 mg, 1.0 mmol), 2-aminoindan (200 mg, 1.5 mmol), and ethanol (6 ml), a similar procedure to Production Example 190 was carried out. The precipitate obtained was crystallized from ethanol to obtain the title compound (100 mg, 0.40 mmol) having the following physical properties:

後処理

  1. customThe precipitate obtained
  2. customwas crystallized from ethanol

出典と根拠

ORDレコード
ord-d42bfccd9ff1439ea1d53148c4cc039d
出典データセット
uspto-grants-2004_03
特許番号
US06703421B1

関連ノート

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