HCID 19748502、化合物 → 2-(1-Aminoethyl)phenol hydrochloride
反応式
[ClH:1].C([O:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[CH:16]([NH2:18])[CH3:17])C1C=CC=CC=1>[Pd].CO>[ClH:1].[OH:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[CH:16]([NH2:18])[CH3:17]参加物
4
実験手順
A mixture obtained by adding 2.64 g of (+)-1-(2-benzyloxyphenyl)ethylamine hydrochloride prepared in Referential Example (3-1) and 0.26 g of 5% Pd-C to 40 ml of methanol was subjected to hydrogenation at room temperature and normal pressure, whereby 256 ml of hydrogen was absorbed. After filtering off the catalyst, the filtrate was concentrated under reduced pressure to give 1.78 g of (+)-1-(2-hydroxyphenyl)ethylamine hydrochloride.
後処理
- customA mixture obtained
- customwas subjected to hydrogenation at room temperature
- customnormal pressure, whereby 256 ml of hydrogen was absorbed
- filtrationAfter filtering off the catalyst
- concentrationthe filtrate was concentrated under reduced pressure
出典と根拠
- ORDレコード
- ord-3cf72baeb0824305838f2c7f7b5f5347
- 出典データセット
- uspto-grants-1993_07
- 特許番号
- US05231227
反応ノート
読み込み中…