N-bromobutanimide → 3'-(Bromomethyl)-2-fluoro-1,1'-biphenyl

HRID 485532ノート

反応式

HRID 485532 の反応式
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([CH3:14])[CH:9]=1.[Br:15]N1C(=O)CCC1=O>C(Cl)(Cl)(Cl)Cl>[Br:15][CH2:14][C:10]1[CH:9]=[C:8]([C:3]2[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=2[F:1])[CH:13]=[CH:12][CH:11]=1

参加物

4

反応物 2

HCID 67184N-bromobutanimideHCID 128530412-Fluoro-3'-methyl-1,1'-biphenyl

生成物 1

HCID 128530423'-(Bromomethyl)-2-fluoro-1,1'-biphenyl収率 81.7%

試薬・触媒・溶媒 1

HCID 5943Carbon Tetrachloride溶媒

実験手順

A mixture of 2'-fluoro-3-methyl[1,1'-biphenyl] (1.1 g, 0.006 mole) and N-bromosuccinimide (1.1 g, 0.006 mole) in 11 ml of carbon tetrachloride was irradiated with white light to afford 3-bromomethyl-2'-fluoro[1,1'-biphenyl] (1.3 g). The nmr spectrum was consistent with that expected for the named compound.

後処理

  1. customwas irradiated with white light

出典と根拠

ORDレコード
ord-be8ce49979bc42aeb00fe1b01493601d
出典データセット
uspto-grants-1985_08
特許番号
US04536591

反応ノート

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