Acetic Anhydride → HCID 19095933、化合物

HRID 486779ノート

反応式

HRID 486779 の反応式
[OH:1][C:2]1[C:7]2=[CH:8][C:9]3[C:14]([N:6]2[CH2:5][CH:4]([C:15]([O:17][CH2:18][CH3:19])=[O:16])[C:3]=1[C:20]([O:22][CH2:23][CH3:24])=[O:21])=[CH:13][CH:12]=[CH:11][CH:10]=3.[C:25](OC(=O)C)(=[O:27])[CH3:26]>N1C=CC=CC=1>[C:25]([O:1][C:2]1[C:7]2=[CH:8][C:9]3[C:14]([N:6]2[CH2:5][CH:4]([C:15]([O:17][CH2:18][CH3:19])=[O:16])[C:3]=1[C:20]([O:22][CH2:23][CH3:24])=[O:21])=[CH:13][CH:12]=[CH:11][CH:10]=3)(=[O:27])[CH3:26]

参加物

4

反応物 2

HCID 7918Acetic AnhydrideHCID 54684685HCID 54684685、化合物

生成物 1

HCID 19095933HCID 19095933、化合物

試薬・触媒・溶媒 1

HCID 1049Pyridine溶媒

実験手順

From a mixture of 29.3 g of diethyl 6,7-dihydro-9-hydroxypyrido[1,2-a]indole-7,8-dicarboxylate, 100 ml of pyridine and 30 ml of acetic anhydride, the solvents were removed under reduced pressure and the residue was partitioned between ethyl acetate and 2M hydrochloric acid. The organic extract was washed with saturated sodium bicarbonate solution and water, dried and evaporated to give 33 g of diethyl 9-acetoxy-6,7-dihydropyrido[1,2-a]indole-7,8-dicarboxylate.

後処理

  1. customthe solvents were removed under reduced pressure
  2. customthe residue was partitioned between ethyl acetate and 2M hydrochloric acid
  3. extractionThe organic extract
  4. washwas washed with saturated sodium bicarbonate solution and water
  5. customdried
  6. customevaporated

出典と根拠

ORDレコード
ord-f40ad0f0844745faa02dbe3e7719ce53
出典データセット
uspto-grants-1994_03
特許番号
US05292747

反応ノート

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