Sodium Hydroxide → HCID 23694526、化合物

HRID 486894ノート

反応式

HRID 486894 の反応式
[O:1]1[C:5]2[CH:6]=[CH:7][C:8]([CH:10]([S:14][CH2:15][C:16]([OH:18])=[O:17])[CH2:11][CH2:12][CH3:13])=[CH:9][C:4]=2[O:3][CH2:2]1.[OH-].[Na+:20]>C(O)C>[O:1]1[C:5]2[CH:6]=[CH:7][C:8]([CH:10]([S:14][CH2:15][C:16]([O-:18])=[O:17])[CH2:11][CH2:12][CH3:13])=[CH:9][C:4]=2[O:3][CH2:2]1.[Na+:20]

参加物

4

反応物 2

HCID 14798Sodium HydroxideHCID 14514901HCID 14514901、化合物

生成物 1

HCID 23694526HCID 23694526、化合物

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

100 g of [{1-(1,3-benzodioxol-5-yl)butyl}thio]acetic acid was dissolved in 500 ml of ethanol. 372 ml of 1N-aqueous sodium hydroxide solution was added thereto. Ethanol and water were removed from the reaction mixture by azeotropic distillation and then ether was added to the residue to solidify it. A precipitate thus formed was recovered by filtration and dried to obtain 102 g of the intended compound in the form of a white powder.

後処理

  1. customEthanol and water were removed from the reaction mixture by azeotropic distillation
  2. additionether was added to the residue
  3. customA precipitate thus formed
  4. filtrationwas recovered by filtration
  5. customdried

出典と根拠

ORDレコード
ord-18f705f540f544ebb07619a87ffbb964
出典データセット
uspto-grants-1994_03
特許番号
US05292901

反応ノート

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