Octanal → 2-Methylene-octanal

HRID 487860

反応式

HRID 487860 の反応式
[CH:1](=[O:9])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].[CH2:10]=O>>[CH2:3]([C:2](=[CH2:10])[CH:1]=[O:9])[CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]

参加物

3

反応物 2

HCID 454OctanalHCID 712Formaldehyde

生成物 1

HCID 112057952-Methylene-octanal収率 38,775.301%

実験手順

100 G (0.78 mmol) of n-octanal, 73 g of 36% formic aldehyde and 260 g (0.78 mol) of catalyst (aqueous diethylamine chlorhydrate; 3 mol/kg) were charged in a 3-neck flask. The mixture was heated to reflux for 1 h and distilled. The reaction product was extracted with ether, dried and concentrated to give 42.41 g of 2-hexyl-2-propenal. Extraction of the flask's residue provided yet 64 g of raw product. The aldehyde was used as such in the next step.

後処理

  1. temperatureThe mixture was heated
  2. temperatureto reflux for 1 h
  3. distillationdistilled
  4. extractionThe reaction product was extracted with ether
  5. customdried
  6. concentrationconcentrated

出典と根拠

ORDレコード
ord-9554cf61c99e458f83aa67612c5cd11c
出典データセット
uspto-grants-1994_03
特許番号
US05298486

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