Sodium Hydroxide → 3,4-Bis(tetradecyloxy)benzoic acid

HRID 488279ノート

反応式

HRID 488279 の反応式
C[O:2][C:3](=[O:40])[C:4]1[CH:9]=[CH:8][C:7]([O:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH3:24])=[C:6]([O:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH3:39])[CH:5]=1.[OH-].[Na+]>CO.O1CCOCC1>[CH2:26]([O:25][C:6]1[CH:5]=[C:4]([CH:9]=[CH:8][C:7]=1[O:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH3:24])[C:3]([OH:40])=[O:2])[CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH3:39]

参加物

5

反応物 2

HCID 14798Sodium HydroxideHCID 120485573,4-Bis(tetradecyloxy)benzoic acid methyl ester

生成物 1

HCID 190162583,4-Bis(tetradecyloxy)benzoic acid収率 73.1%

試薬・触媒・溶媒 2

HCID 887Methanol溶媒HCID 312751,4-Dioxane溶媒

実験手順

A solution of 3,4-bis(tetradecyloxy)benzoic acid methyl ester (1.1 g, 2.0 mmol) and 1.6 ml (9.6 mmol) of 6N NaOH in 40 ml of methanol and 20 ml of dioxane was stirred at reflux for 17 hours. The solvents were removed at reduced pressure, the residue was acidified and the solid was filtered and recrystallized from methanol-THF-water to give 0.8 g (73% yield, mp 112°-113°) of 3,4-bis(tetradecyloxy)benzoic acid.

後処理

  1. temperatureat reflux for 17 hours
  2. customThe solvents were removed at reduced pressure
  3. filtrationthe solid was filtered
  4. customrecrystallized from methanol-THF-water

出典と根拠

ORDレコード
ord-e56c65918aec4bc69d906b45b9df40bb
出典データセット
uspto-grants-1994_03
特許番号
US05298652

反応ノート

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