2,5-bis(4-methylbenzoyl)terephthalic Acid → 2,5-Bis(4-methylbenzyl)terephthalic acid

HRID 488948ノート

反応式

HRID 488948 の反応式
[CH3:1][C:2]1[CH:30]=[CH:29][C:5]([C:6]([C:8]2[CH:16]=[C:15]([C:17]([OH:19])=[O:18])[C:14]([C:20](=O)[C:21]3[CH:26]=[CH:25][C:24]([CH3:27])=[CH:23][CH:22]=3)=[CH:13][C:9]=2[C:10]([OH:12])=[O:11])=O)=[CH:4][CH:3]=1.[H][H]>[Pd].C(O)(=O)C>[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:6][C:8]2[CH:16]=[C:15]([C:17]([OH:19])=[O:18])[C:14]([CH2:20][C:21]3[CH:22]=[CH:23][C:24]([CH3:27])=[CH:25][CH:26]=3)=[CH:13][C:9]=2[C:10]([OH:12])=[O:11])=[CH:29][CH:30]=1

参加物

5

反応物 2

HCID 112581482,5-bis(4-methylbenzoyl)terephthalic AcidHCID 178418361HCID 178418361、化合物

生成物 1

HCID 117491572,5-Bis(4-methylbenzyl)terephthalic acid

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 176Acetic Acid溶媒

実験手順

A mixture of 30.0 grams of 2,5-bis(4-methylbenzoyl)terephthalic acid, 500 mL of acetic acid, and 3 grams of 5% palladium on activated carbon (as a catalyst) was heated to 64° C. for 17 hours in an atmosphere of hydrogen at 270 kPa. The mixture was filtered to remove the catalyst and the product. The catalyst and the product were slurried in 500 mL of tetrahhydrofuran and filtered through Celite™ diatomaceous earth filter agent. The resulting filtrate was concentrated in vacuo. The resulting wet solid was slurried in ethyl acetate and collected by filtration and dried to give 2,5-bis(4-methylbenzyl)terephthalic acid.

後処理

  1. filtrationThe mixture was filtered
  2. customto remove the catalyst
  3. filtrationfiltered through Celite™ diatomaceous earth
  4. filtrationfilter agent
  5. concentrationThe resulting filtrate was concentrated in vacuo
  6. filtrationcollected by filtration
  7. customdried

出典と根拠

ORDレコード
ord-6d8fde46ea5f4333aa8ec5532b4ba027
出典データセット
uspto-grants-2005_12
特許番号
US06974877B2

反応ノート

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