3-Aminopyridine → 2-Oxo-2,3-dihydro-1H-indole-5-sulfonic acid pyridin-3-ylamide
反応式
Cl[S:2]([C:5]1[CH:6]=[C:7]2[C:11](=[CH:12][CH:13]=1)[NH:10][C:9](=[O:14])[CH2:8]2)(=[O:4])=[O:3].[NH2:15][C:16]1[CH:17]=[N:18][CH:19]=[CH:20][CH:21]=1>N1C=CC=CC=1>[N:18]1[CH:19]=[CH:20][CH:21]=[C:16]([NH:15][S:2]([C:5]2[CH:6]=[C:7]3[C:11](=[CH:12][CH:13]=2)[NH:10][C:9](=[O:14])[CH2:8]3)(=[O:4])=[O:3])[CH:17]=1参加物
4
実験手順
A solution of 5-chlorosulfonyl-2-oxindole (3 g) and 3-aminopyridine (1.46 g) in pyridine (15 mL) was stirred at room temperature for overnight at which time the brown color solid was present. The precipitate was filtered, washed with ethanol and dried under vacuum to yield 1.4 g (38%) of 2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid pyridin-3-ylamide.
後処理
- filtrationThe precipitate was filtered
- washwashed with ethanol
- customdried under vacuum
出典と根拠
- ORDレコード
- ord-a448c9033e3b427486cb7abc44de8ab3
- 出典データセット
- uspto-grants-2004_03
- 特許番号
- US06706709B2
反応ノート
読み込み中…