反応式
[NH2:1][C:2]1[CH:18]=[CH:17][C:5]([O:6][C:7]2[CH:8]=[C:9]([CH:14]=[CH:15][CH:16]=2)[C:10]([NH:12][CH3:13])=[O:11])=[CH:4][C:3]=1[N+:19]([O-])=O>CO.[Pd]>[NH2:19][C:3]1[CH:4]=[C:5]([CH:17]=[CH:18][C:2]=1[NH2:1])[O:6][C:7]1[CH:8]=[C:9]([CH:14]=[CH:15][CH:16]=1)[C:10]([NH:12][CH3:13])=[O:11]参加物
4
実験手順
3-(4-Amino-3-nitro-phenoxy)-N-methyl-benzamide (Step B, 0.5 g, 1.7 mmol, 1.0 eq.) was dissolved in MeOH (10 mL) and the atmosphere was replaced by argon. A catalytic amount of 10% Pd/C was added and the argon was replaced by a H2 atmosphere. The mixture was stirred for 16 h at RT at atmospheric pressure. The Pd/C was filtered off and the obtained 3-(3,4-diamino-phenoxy)-N-methyl-benzamide was used crude in the next step.
後処理
- filtrationThe Pd/C was filtered off
出典と根拠
- ORDレコード
- ord-41fde00c3b9b42b1b5c8233aa1c204c5
- 出典データセット
- uspto-grants-2009_05
- 特許番号
- US07531553B2
関連ノート
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