5-Aminovaleric acid → Methyl 5-aminopentanoate hydrochloride

5-Aminovaleric acid (7.35 g) is dissolved in methanol (50 ml), thereto is added dropwise thionyl chloride (4.9 ml) under ice-cooling, and the reaction solution is warmed to room temperature and stirred for 17 hours. The reaction solution is concentrated under reduced pressure, and the resulting residue is suspended in diethyl ether and the precipitates are collected by filtration to give methyl 5-aminovalerate hydrochloride (9.93 g).

1. temperaturecooling
2. concentrationThe reaction solution is concentrated under reduced pressure
3. filtrationthe precipitates are collected by filtration

ORDレコード

ord-a2828dee971c45bdae4a7aedd612643c

出典データセット

uspto-grants-2009_05

DOI

10.6084/m9.figshare.5104873.v1

特許番号

US07531537B2