関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Hydrogen Bromide | HCID 260 | — |
| 反応物 | 4-Methoxy-4'-nitrobiphenyl | HCID 11128079 | — |
| 溶媒 | Acetic Acid | HCID 176 | — |
| 生成物 | 4-Hydroxy-4'-nitrobiphenyl | HCID 138078 | — |
反応手順
4′-Methoxy-4-nitro-biphenyl (4.55 g, 19.8 mmol), prepared in the previous step, in a mixture of glacial acetic acid plus 65 mL of 48% HBr was heated at approximately 120° C. until the reaction was complete by TLC. The reaction was concentrated under reduced pressure and the residue partitioned between diethyl ether and water. The organic layer was separated, dried (Na2SO4) and the solvent removed under reduced pressure to give 4′-hydroxy-4-nitro-biphenyl.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US07534894B2 |
|---|
| 出典データセット | uspto-grants-2009_05 |
|---|
| ORD ID | ord-b96104b8c75c422aacbc263d6a4065c5 |
|---|
| 出典メモ | uspto-grants-2009_05 |
|---|
