Ethanol → 2(1H)-Quinoxalinone

HRID 493976

反応式

HRID 493976 の反応式
[C:1]1([NH2:8])[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[NH2:7].[CH3:9][CH2:10][OH:11]>>[NH:7]1[C:2]2[C:1](=[CH:6][CH:5]=[CH:4][CH:3]=2)[N:8]=[CH:9][C:10]1=[O:11]

参加物

3

反応物 2

HCID 702EthanolHCID 7243O-Phenylenediamine

生成物 1

HCID 145262(1H)-Quinoxalinone

実験手順

A mixture of the 1,2-phenylene-diamine derivative (1 g) and the 2-oxo-carboxylic acid derivative (1 eq) in dry EtOH (35 mL) was stirred at reflux for 2 h under nitrogen. After cooling, the EtOH was evaporated to give a crude brown solid. Recrystallisation from EtOH gave the desired quinoxalin-2-one derivative.

後処理

  1. temperatureat reflux for 2 h under nitrogen
  2. temperatureAfter cooling
  3. customthe EtOH was evaporated
  4. customto give a crude brown solid
  5. customRecrystallisation from EtOH

出典と根拠

ORDレコード
ord-e11bf6e15ac14fa9a03e91a18f60a7dd
出典データセット
uspto-grants-2009_05
特許番号
US07538109B2

関連ノート

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