Diethyl Malonate → Dimethyl 2-(2-isopentyl-5-methyl-2-phenylhexanoyl)malonate
反応式
[C:1]([O:9][CH2:10]C)(=[O:8])[CH2:2][C:3]([O:5][CH2:6]C)=[O:4].[CH2:12]([C:17]([C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1)([CH2:21][CH2:22][CH:23]([CH3:25])[CH3:24])[C:18](Cl)=[O:19])[CH2:13][CH:14]([CH3:16])[CH3:15].C1(C(CCC)(CCC)C(Cl)=O)C=CC=CC=1>>[CH2:12]([C:17]([C:26]1[CH:27]=[CH:28][CH:29]=[CH:30][CH:31]=1)([CH2:21][CH2:22][CH:23]([CH3:24])[CH3:25])[C:18]([CH:2]([C:1]([O:9][CH3:10])=[O:8])[C:3]([O:5][CH3:6])=[O:4])=[O:19])[CH2:13][CH:14]([CH3:16])[CH3:15]参加物
4
実験手順
The title compound was prepared following the procedure of Example 1E, substituting dimethyl malonate for diethyl malonate, and substituting the product of Example 6D for the product of Example 1D. 1H NMR (300 MHz, CDCl3): δ 7.32 (m, 5 H), 4.54 (s, 1 H), 3.56 (s, 6 H), 2.00 (m, 4 H), 1.49 (m, 2 H), 0.87 (m, 16 H).