反応式
[CH:1]12[CH2:7][CH:4]([CH2:5][CH2:6]1)[CH2:3][CH:2]2[CH2:8][OH:9].C1C=C[NH+]=CC=1.[O-][Cr](Cl)(=O)=O>C(Cl)Cl>[CH:1]12[CH2:7][CH:4]([CH2:5][CH2:6]1)[CH2:3][CH:2]2[CH:8]=[O:9]参加物
4
反応条件
- 温度
- 2.5 °C
実験手順
A stirred suspension of 2-norbornylmethanol (0.5 ml; 5.8 mmol) and PCC on Al2O3* in CH2Cl2 (25 ml) was stirred at 2-3° C. for 1 h and allowed to slowly warm up to rt. The reaction mixture was filtered and the solid material washed with CH2Cl2 (2×25 ml). The combined organic fractions were adsorbed onto silica and chromatographed to give 300 mg (42%) product as an oil.
後処理
- temperatureto slowly warm up to rt
- filtrationThe reaction mixture was filtered
- washthe solid material washed with CH2Cl2 (2×25 ml)
- customchromatographed
出典と根拠
- ORDレコード
- ord-99da1fecffe54b5291694c2e35173483
- 出典データセット
- uspto-grants-2005_09
- 特許番号
- US06943159B1
関連ノート
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