Hydrochloric Acid → 5-Oxo-5-phenylpentyl phenoxyacetate

HRID 498144ノート

反応式

HRID 498144 の反応式
Cl.[O:2]([CH2:9][C:10]([O:12][CH2:13][CH2:14][CH2:15][CH2:16][C:17]1([C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)OCC[O:18]1)=[O:11])[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.CCCCCCC.CCOCC>C1COCC1>[O:2]([CH2:9][C:10]([O:12][CH2:13][CH2:14][CH2:15][CH2:16][C:17](=[O:18])[C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)=[O:11])[C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][CH:8]=1

参加物

5

反応物 3

HCID 313Hydrochloric AcidHCID 21897273Diethylether heptaneHCID 223208964-(2-Phenyl-1,3-dioxolan-2-yl)butyl phenoxyacetate

生成物 1

HCID 223209075-Oxo-5-phenylpentyl phenoxyacetate

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒

実験手順

This compound was synthesised as described under 1.e) with 1.45 ml of a 1N solution of HCl, 2.90 g (8.1 mmol) of 4-(2-phenyl-1,3-dioxolan-2-yl)butyl phenoxyacetate obtained under a) in 13 ml of THF for 17 h. Column chromatography (SiO2, heptane/ether 8:2) afforded 1.98 g (78%) of a slightly yellow oil.

後処理

  1. customThis compound was synthesised

出典と根拠

ORDレコード
ord-61be5225119d40efa18ea5b65e514286
出典データセット
uspto-grants-2005_09
特許番号
US06949680B2

反応ノート

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