(4-Fluoro-2-nitro-phenyl)-carbamic acid tert-butyl ester → N1-(tert-Butoxycarbonyl)-4-fluoro-1,2-phenylenediamine
反応式
[C:1]([O:5][C:6](=[O:18])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([F:14])=[CH:10][C:9]=1[N+:15]([O-])=O)([CH3:4])([CH3:3])[CH3:2]>[Pd]>[C:1]([O:5][C:6](=[O:18])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([F:14])=[CH:10][C:9]=1[NH2:15])([CH3:4])([CH3:2])[CH3:3]参加物
3
実験手順
The title compound was prepared from (4-fluoro-2-nitro-phenyl)-carbamic acid tert-butyl ester (Example A3) (32.54 g, 127 mmol) by hydrogenation with 10% Pd/C according to the general procedure J (method a). Obtained as a light orange solid (25.03 g).
出典と根拠
- ORDレコード
- ord-074299a5d2b84d919b29a8e55ecc7135
- 出典データセット
- uspto-grants-2005_09
- 特許番号
- US06949542B2
反応ノート
読み込み中…