tert-Butyl (2-nitro-4-(trifluoromethyl)phenyl)carbamate → tert-butyl N-(2-amino-4-(trifluoromethyl)phenyl)carbamate
反応式
[C:1]([O:5][C:6](=[O:21])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([C:14]([F:17])([F:16])[F:15])=[CH:10][C:9]=1[N+:18]([O-])=O)([CH3:4])([CH3:3])[CH3:2]>[Pd]>[C:1]([O:5][C:6](=[O:21])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([C:14]([F:17])([F:16])[F:15])=[CH:10][C:9]=1[NH2:18])([CH3:4])([CH3:2])[CH3:3]参加物
3
実験手順
The title compound was prepared from (2-nitro-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester (Example A4) (30.0 g, 98 mmol) by hydrogenation with 10% Pd/C according to the general procedure J (method a). Obtained as a light yellow solid (26.5 g).
出典と根拠
- ORDレコード
- ord-5de8fb443640430ebc5c94615725dcf3
- 出典データセット
- uspto-grants-2005_09
- 特許番号
- US06949542B2
反応ノート
読み込み中…