(4-Chloro-5-fluoro-2-nitro-phenyl)-carbamic acid tert-butyl ester → tert-Butyl (2-amino-4-chloro-5-fluorophenyl)carbamate
反応式
[C:1]([O:5][C:6](=[O:19])[NH:7][C:8]1[CH:13]=[C:12]([F:14])[C:11]([Cl:15])=[CH:10][C:9]=1[N+:16]([O-])=O)([CH3:4])([CH3:3])[CH3:2]>[Pt]>[C:1]([O:5][C:6](=[O:19])[NH:7][C:8]1[CH:13]=[C:12]([F:14])[C:11]([Cl:15])=[CH:10][C:9]=1[NH2:16])([CH3:4])([CH3:2])[CH3:3]参加物
3
実験手順
The title compound was prepared from (4-chloro-5-fluoro-2-nitro-phenyl)-carbamic acid tert-butyl ester (Example A6) (16.48 g, 56.7 mmol) by hydrogenation with 5% Pt/C according to the general procedure J (method a). Obtained as a brown solid (14.78 g).
出典と根拠
- ORDレコード
- ord-7a092a66c7cf4cacac512288c4178497
- 出典データセット
- uspto-grants-2005_09
- 特許番号
- US06949542B2
反応ノート
読み込み中…