(2-Nitro-4-trifluoromethoxy-phenyl)-carbamic acid tert-butyl ester → Carbamic acid,[2-amino-4-(trifluoromethoxy)phenyl]-,1,1-dimethylethyl ester

HRID 498213

反応式

HRID 498213 の反応式
[C:1]([O:5][C:6](=[O:22])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([O:14][C:15]([F:18])([F:17])[F:16])=[CH:10][C:9]=1[N+:19]([O-])=O)([CH3:4])([CH3:3])[CH3:2]>[Pd]>[C:1]([O:5][C:6](=[O:22])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([O:14][C:15]([F:18])([F:17])[F:16])=[CH:10][C:9]=1[NH2:19])([CH3:4])([CH3:2])[CH3:3]

参加物

3

反応物 1

HCID 69489589(2-Nitro-4-trifluoromethoxy-phenyl)-carbamic acid tert-butyl ester

生成物 1

HCID 69489489Carbamic acid,[2-amino-4-(trifluoromethoxy)phenyl]-,1,1-dimethylethyl ester

試薬・触媒・溶媒 1

HCID 23938Palladium触媒

実験手順

The title compound was prepared from (2-nitro-4-trifluoromethoxy-phenyl)-carbamic acid tert-butyl ester (Example A22) (10.38 g, 32.2 mmol) by hydrogenation with 10% Pd/C according to the general procedure J (method a). Obtained as a light brown solid (8.76 g, 93%).

出典と根拠

ORDレコード
ord-2fac2924806b4032976ad77bf9f8f930
出典データセット
uspto-grants-2005_09
特許番号
US06949542B2

関連ノート

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