関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Acetyl chloride | HCID 6367 | — |
| 反応物 | 4-Propylanisole | HCID 7702 | — |
| 反応物 | Aluminum(III) Chloride | HCID 6451240 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | 1-(2-Methoxy-5-propylphenyl)ethanone | HCID 68454475 | — |
反応手順
A suspension of 10.6 g of AlCl3 in 150 ml of dichloromethane is cooled to −10° C. 5.7 ml of AcCl and 6 g of 4-propylanisole are added. The medium is stirred at −10° C. for 30 min, and then poured into a beaker containing ice mixed with 35% HCl. After separation by settling out, the aqueous phase is extracted 3 times in dichloromethane, and the combined organic phases are washed with water and with a saturated NaCl solution, dried over MgSO4 and then evaporated, to give 7.86 g of a brown oil (quant.).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US07767681B2 |
|---|
| 出典データセット | uspto-grants-2010_08 |
|---|
| ORD ID | ord-ff7b12e1e5114d81b9ff79a24e6944c5 |
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| 出典メモ | uspto-grants-2010_08 |
|---|
