反应详情

温度

-10 °C

A suspension of 10.6 g of AlCl3 in 150 ml of dichloromethane is cooled to −10° C. 5.7 ml of AcCl and 6 g of 4-propylanisole are added. The medium is stirred at −10° C. for 30 min, and then poured into a beaker containing ice mixed with 35% HCl. After separation by settling out, the aqueous phase is extracted 3 times in dichloromethane, and the combined organic phases are washed with water and with a saturated NaCl solution, dried over MgSO4 and then evaporated, to give 7.86 g of a brown oil (quant.).

1. additionpoured into a beaker
2. additioncontaining ice
3. customAfter separation
4. extractionthe aqueous phase is extracted 3 times in dichloromethane
5. washthe combined organic phases are washed with water and with a saturated NaCl solution
6. dry with materialdried over MgSO4
7. customevaporated