Hydrochloric Acid → 6-Quinolinecarboxylic acid, ethyl ester
反応式
[N:1]1[C:10]2[C:5](=[CH:6][C:7]([C:11]([OH:13])=[O:12])=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1.O1CCO[CH2:16][CH2:15]1.Cl>C(O)C>[N:1]1[C:10]2[C:5](=[CH:6][C:7]([C:11]([O:13][CH2:15][CH3:16])=[O:12])=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1参加物
5
反応条件
- 温度
- 70 °C
実験手順
4.9 g of quinoline-6-carboxylic acid was stirred in 80 ml of ethanol. 40 ml of dioxane containing 4 M of hydrogen chloride was added to the obtained mixture. After stirring at 70° C. overnight, the solvent was evaporated and the residue was treated with ethyl acetate as the extracting solvent by an ordinary method to obtain the title compound.
後処理
- customthe solvent was evaporated
- additionthe residue was treated with ethyl acetate as the extracting solvent by an ordinary method
出典と根拠
- ORDレコード
- ord-39bdd5917a824cf489af4d15fa464529
- 出典データセット
- uspto-grants-2004_03
- 特許番号
- US06710056B2
反応ノート
読み込み中…