Methyl iodide → Methyl 5-iodo-2-methoxybenzoate

HRID 49947ノート

反応式

HRID 49947 の反応式
CI.[I:3][C:4]1[CH:13]=[C:8]([C:9]([O:11][CH3:12])=[O:10])[C:7]([OH:14])=[CH:6][CH:5]=1.[C:15](=O)([O-])[O-].[K+].[K+]>CN(C)C=O>[CH3:15][O:14][C:7]1[CH:6]=[CH:5][C:4]([I:3])=[CH:13][C:8]=1[C:9]([O:11][CH3:12])=[O:10]

参加物

5

反応物 3

HCID 6328Methyl iodideHCID 11430Potassium CarbonateHCID 248910Methyl 5-Iodosalicylate

生成物 1

HCID 11011762Methyl 5-iodo-2-methoxybenzoate

試薬・触媒・溶媒 1

HCID 6228Dimethylformamide溶媒

実験手順

Methyl iodide (0.29 ml, 4.68 mmol) was added to a mixture of 1.0 g (3.60 mmol) of methyl 5-iodosalicylate, 0.50 g (3.60 mmol) of potassium carbonate and 4 ml of dimethylformamide, and they were stirred at room temperature for 3 hours. The reaction mixture was filtered through Celite and then after-treated in by an ordinary method to obtain the title compound.

後処理

  1. filtrationThe reaction mixture was filtered through Celite
  2. additionafter-treated in by an ordinary method

出典と根拠

ORDレコード
ord-fa15a67265c94805a97b2ae90bc289f0
出典データセット
uspto-grants-2004_03
特許番号
US06710056B2

反応ノート

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