Acetic Anhydride → 3-(2-Pyridyl)propyl acetate
反応式
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[CH2:7][CH2:8][CH2:9][OH:10].[C:11](OC(=O)C)(=[O:13])[CH3:12]>N1C=CC=CC=1>[C:11]([O:10][CH2:9][CH2:8][CH2:7][C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][N:1]=1)(=[O:13])[CH3:12]参加物
4
実験手順
2-Pyridinepropanol (2.0 g, 14.6 mmol) was dissolved in pyridine (5 ml), and acetic anhydride (3.0 g, 29.2 mmol) was added thereto. The reaction mixture was stirred at room temperature for 2.5 hrs, and subjected to a silica gel (75 g) column chromatography. The fractions eluted with hexane-ethyl acetate (3:1, v/v) were collected and concentrated to give the titled compound (2.6 g, 99%).
後処理
- washThe fractions eluted with hexane-ethyl acetate (3:1
- customv/v) were collected
- concentrationconcentrated
出典と根拠
- ORDレコード
- ord-c448b787721b4073b3743c225cff8fc7
- 出典データセット
- uspto-grants-2010_08
- 特許番号
- US07767665B2
反応ノート
読み込み中…