γ-Methylene-6-quinolinepropanol → HCID 67223946、化合物
反応式
[N:1]1[C:10]2[C:5](=[CH:6][C:7]([C:11](=[CH2:15])[CH2:12][CH2:13][OH:14])=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1>[Pt].CO>[N:1]1[C:10]2[C:5](=[CH:6][C:7]([CH:11]([CH3:15])[CH2:12][CH2:13][OH:14])=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1参加物
4
実験手順
A mixture of 3-quinolin-6-ylbut-3-en-1-ol (1.0 g, 0.0050 mol), platinum on carbon (5 wt. % supported on activated carbon, wet, Degussa type F100 ra/w, 0.20 g) in methanol (15.0 mL) was stirred under hydrogen (with a balloon) at RT for 5 h. The mixture was filtered and the filtrate was concentrated to give the desired product (1.0 g, 99%). LCMS: (M+H)=202.1.
後処理
- filtrationThe mixture was filtered
- concentrationthe filtrate was concentrated
出典と根拠
- ORDレコード
- ord-870f3f119b58457db736f49ad5537b7c
- 出典データセット
- uspto-grants-2010_08
- 特許番号
- US07767675B2
反応ノート
読み込み中…