3,5-Dimethylisoxazole-4-isocyanate → 1-(3,5-Dimethylisoxazol-4-yl)carbamoylcyclopropanesulfonamide tert-butylcarbamate

HRID 500332

反応式

HRID 500332 の反応式
[C:1]([NH:5][C:6](=[O:8])[OH:7])([CH3:4])([CH3:3])[CH3:2].C[O:10][CH2:11][C:12]1([S:15]([NH2:18])(=[O:17])=[O:16])[CH2:14][CH2:13]1.[CH3:19][C:20]1[O:24][N:23]=[C:22]([CH3:25])[C:21]=1[N:26]=C=O>>[C:1]([NH:5][C:6](=[O:7])[OH:8])([CH3:4])([CH3:3])[CH3:2].[CH3:25][C:22]1[C:21]([NH:26][C:11]([C:12]2([S:15]([NH2:18])(=[O:17])=[O:16])[CH2:14][CH2:13]2)=[O:10])=[C:20]([CH3:19])[O:24][N:23]=1

参加物

3

反応物 2

HCID 27362663,5-Dimethylisoxazole-4-isocyanateHCID 667523821-Methoxymethylcyclopropylsulfonylamine tert-butylcarbamate

生成物 1

HCID 667524801-(3,5-Dimethylisoxazol-4-yl)carbamoylcyclopropanesulfonamide tert-butylcarbamate収率 100%

実験手順

This compound was obtained in a crude 100% yield according to the procedure described for the synthesis of 1-methoxymethylcyclopropylsulfonylamine tert-butylcarbamate except that 1.20 equivalents of 3,5-dimethylisoxazole-4-isocyanate was used as the electrophile. The compound was taken directly into the next reaction without purification.

後処理

  1. customThis compound was obtained in a crude 100% yield
  2. customThe compound was taken directly into the next reaction without purification

出典と根拠

ORDレコード
ord-ff598d96d2ea4b16b39088dd92608f84
出典データセット
uspto-grants-2010_08
特許番号
US07772180B2

関連ノート

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