Phenol → 4'-Phenoxyacetophenone

HRID 501267

反応式

HRID 501267 の反応式
[C:1]1([OH:7])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:8][C:9](N(C)C)=[O:10]>>[CH3:8][C:9]([C:4]1[CH:5]=[CH:6][C:1]([O:7][C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)=[CH:2][CH:3]=1)=[O:10]

参加物

3

反応物 2

HCID 996PhenolHCID 31374Dimethylacetamide

生成物 1

HCID 2367834'-Phenoxyacetophenone

実験手順

4-Phenoxyacetophenone was prepared by refluxing 4-fluoroaceotone and phenol in DMAc for 16 hours. The solvent was removed under reduced pressure and the reside subjected to standard ethyl acetate/water work-up and the resulting material purified by silica gel chromatography.

後処理

  1. temperatureby refluxing 4-fluoroaceotone
  2. customThe solvent was removed under reduced pressure
  3. customthe resulting material purified by silica gel chromatography

出典と根拠

ORDレコード
ord-2336461666234a08953253d8164eb22e
出典データセット
uspto-grants-2010_08
特許番号
US07772260B2

関連ノート

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