1,1-Dibromoethane → HCID 178497629、化合物
反応式
[Zn:1].[Br:2]C(Br)C.[CH3:6][O:7][C:8](=[O:17])[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[CH2:15]Br>C1COCC1>[Br-:2].[C:8]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[CH2:15][Zn+:1])([O:7][CH3:6])=[O:17]参加物
5
反応条件
- 温度
- 60 °C
実験手順
Under atmosphere of argon, to a solution of zinc powder (1.89 g) in anhydrous THF (15 ml) was added dibromoethane (116 ul) and the mixture was stirred for five minutes at 60° C. To the reaction mixture was added a solution of 2-bromomethylbenzoic acid methyl ester (4.42 g) in anhydrous THF (15 ml) over a period of 30 minutes at 0° C. and the mixture was stirred for 2 hours at the temperature to give a 2-carbomethoxybenzylzinc (II) bromide (benzyl zinc) solution.
後処理
- stirringthe mixture was stirred for 2 hours at the temperature
出典と根拠
- ORDレコード
- ord-3d85f2e4c29643f2af3cd20c5f177c58
- 出典データセット
- uspto-grants-2004_03
- 特許番号
- US06710205B2
反応ノート
読み込み中…