Thionyl Chloride → Cyclohexanecarbonyl chloride, 5-methyl-2-(1-methylethyl)-

反応式

[CH:1]1([CH3:13])[CH2:6][CH2:5][CH:4]([CH:7]([CH3:9])[CH3:8])[CH:3]([C:10](O)=[O:11])[CH2:2]1.S(Cl)([Cl:16])=O>>[CH:1]1([CH3:13])[CH2:6][CH2:5][CH:4]([CH:7]([CH3:9])[CH3:8])[CH:3]([C:10]([Cl:16])=[O:11])[CH2:2]1

参加物

反応物 2

HCID 24386Thionyl Chloride

HCID 97896p-Menthane-3-carboxylic acid

生成物 1

HCID 13734319Cyclohexanecarbonyl chloride, 5-methyl-2-(1-methylethyl)-

実験手順

Menthane-3-carboxylic acid (54.35 g) was refluxed with 80 ml of thionyl chloride for 3 hours. The SOCl2 was removed by distillation, and the acid chloride was distilled at 114-115° C. (8 Torr). (Lit. b.p. 84-85° C. at 3.5 Torr). Yield: 50 g (84%).

後処理

customThe SOCl2 was removed by distillation
distillationthe acid chloride was distilled at 114-115° C. (8 Torr)

出典と根拠

ORDレコード: ord-5e679ed1197e4f6993315a06adb1d0ef
出典データセット: uspto-grants-2010_08
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07772266B2

反応ノート

読み込み中…

参加物