Trifluoroacetic acid → HCID 86609552、化合物
反応式
C(OC([N:8]1[CH2:13][CH2:12][CH:11]([NH:14][C:15](=[O:27])[C:16]2[CH:21]=[CH:20][CH:19]=[C:18]([O:22][S:23]([CH3:26])(=[O:25])=[O:24])[CH:17]=2)[CH2:10][CH2:9]1)=O)(C)(C)C.FC(F)(F)C(O)=O>C(Cl)Cl>[NH:8]1[CH2:13][CH2:12][CH:11]([NH:14][C:15]([C:16]2[CH:17]=[C:18]([O:22][S:23]([CH3:26])(=[O:24])=[O:25])[CH:19]=[CH:20][CH:21]=2)=[O:27])[CH2:10][CH2:9]1参加物
4
実験手順
The above prepared 4-(3-methanesulfonyloxy-benzoylamino)-piperidine-1-carboxylic acid tert-butyl ester (0.920 g, 1.85 mmol) was dissolved in 9.5 ml of CH2Cl2 and treated with 2.4 ml of trifluoroacetic acid. After stirring for 4 h at ambient temperature, TLC indicated the absence of starting material. Evaporation of all volatiles left 1.47 g of the title compound as trifluoroacetate as off-white viscous oil.
後処理
- custom