Oxalyl chloride → 3,5-Di-t-butylbenzoyl chloride

HRID 502790

反応式

HRID 502790 の反応式
[C:1](Cl)(=O)[C:2]([Cl:4])=[O:3].[C:7]([C:11]1[CH:12]=C([CH:17]=[C:18]([C:20]([CH3:23])([CH3:22])[CH3:21])[CH:19]=1)C(O)=O)([CH3:10])([CH3:9])[CH3:8]>CN(C)C=O.ClCCl>[C:20]([C:18]1[CH:17]=[C:1]([CH:12]=[C:11]([C:7]([CH3:10])([CH3:9])[CH3:8])[CH:19]=1)[C:2]([Cl:4])=[O:3])([CH3:23])([CH3:22])[CH3:21]

参加物

5

反応物 2

HCID 65578Oxalyl chlorideHCID 853393,5-Bis(tert-butyl)benzoic acid

生成物 1

HCID 118176223,5-Di-t-butylbenzoyl chloride

試薬・触媒・溶媒 2

HCID 6228Dimethylformamide触媒HCID 6344Dichloromethane溶媒

実験手順

Oxalyl chloride (0.542 g, 0.37 ml, 4.27 mmol) was added dropwise to a solution of 3,5-di-tert-butylbenzoic acid (0.200 g, 0.853 mmol) and dichloromethane (4 ml). N,N-Dimethylformamide (1 drop) was added and the colorless solution stirred at RT for 3 h. The solution was concentrated to afford 3,5-di-tert-butylbenzoyl chloride as a yellow oil.

後処理

  1. concentrationThe solution was concentrated

出典と根拠

ORDレコード
ord-992d23101f33403e8fa8cd7dad5e4beb
出典データセット
uspto-grants-2010_08
特許番号
US07776869B2

関連ノート

読み込み中…