Dichloromethane → HCID 9397001、化合物
反応式
[NH:1]1[CH2:6][CH2:5][NH:4][CH2:3][C:2]1=[O:7].ClCCl.O1CCOCC1.[C:17]1([S:23](Cl)(=[O:25])=[O:24])[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>N1C=CC=CC=1>[C:17]1([S:23]([N:4]2[CH2:5][CH2:6][NH:1][C:2](=[O:7])[CH2:3]2)(=[O:25])=[O:24])[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1参加物
6
実験手順
2-piperazinone was suspended in a mixed solvent of dichloromethane and dioxane and then pyridine and benzenesulfonyl chloride were added thereto. After stirring at room temperature for 16 hours, the solvent was removed by evaporation and the resulting solid was suspended in 1N hydrochloric acid, filtered, and washed with diisopropyl ether to obtain 4-(phenylsulfonyl)-2-piperazinone.
後処理
- customthe solvent was removed by evaporation
- filtrationfiltered
- washwashed with diisopropyl ether
出典と根拠
- ORDレコード
- ord-2cae02dca9454d9d85e66c87278e51b3
- 出典データセット
- uspto-grants-2010_08
- 特許番号
- US07776897B2
反応ノート
読み込み中…