Hydrazine hydrate (1:1) → 1H-pyrrole-2-carbohydrazonamide
反応式
[NH:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]#[N:7].C[O-].[Na+].O.[NH2:12][NH2:13]>C(O)C.O>[NH:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6](=[N:12][NH2:13])[NH2:7]参加物
6
実験手順
A solution of 10 g 1H-pyrrole-2-carbonitrile and 1 eq sodium methoxide in 20 ml ethanol and stirred for 10 min. Hydrazine hydrate (3 eq.) is then added and resulting reaction mixture is stirred at room temperature for 18 h. The Reaction mixture is then diluted with water, extracted with ethyl acetate, dried over Na2SO4 and concentrated under vacuum to yield desired compound.
後処理
- customresulting
- customreaction mixture
- extractionextracted with ethyl acetate
- dry with materialdried over Na2SO4
- concentrationconcentrated under vacuum
出典と根拠
- ORDレコード
- ord-e3f6ae66f714449492a1fc650b79c8ba
- 出典データセット
- uspto-grants-2010_08
- 特許番号
- US07776864B2
反応ノート
読み込み中…