HCID 178498471、化合物 → Methyl 5-amino-1H-pyrazole-3-carboxylate

HRID 503807ノート

反応式

HRID 503807 の反応式
[N+:1]([C:4]1[CH:8]=[C:7]([C:9]([O:11][CH3:12])=[O:10])[NH:6][N:5]=1)([O-])=O>CO.[Pd]>[NH2:1][C:4]1[CH:8]=[C:7]([C:9]([O:11][CH3:12])=[O:10])[NH:6][N:5]=1

参加物

4

反応物 1

HCID 178498471HCID 178498471、化合物

生成物 1

HCID 18445864Methyl 5-amino-1H-pyrazole-3-carboxylate

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 887Methanol溶媒

実験手順

To 14.0 g methyl 3-nitro-1H-pyrazole-5-carboxylate in 200 ml methanol are added 1.2 g Pd/C (10% w/w). The mixture is stirred under H2-atmosphere at room temperature for 18 h. The mixture is filtrated over kieselgur. The filtrate is concentrated and the crude product is used without further purification.

後処理

  1. filtrationThe mixture is filtrated over kieselgur
  2. concentrationThe filtrate is concentrated
  3. customthe crude product is used without further purification

出典と根拠

ORDレコード
ord-14c9a9a466c94fd7a85eadc43ac130ca
出典データセット
uspto-grants-2010_08
特許番号
US07776864B2

反応ノート

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