Pyridine → HCID 57750155、化合物
反応式
[OH:1][CH2:2][C:3]1([C:8]#[N:9])[CH2:7][CH2:6][CH2:5][CH2:4]1.N1C=CC=CC=1.[C:16]1([CH3:26])[CH:21]=[CH:20][C:19]([S:22](Cl)(=[O:24])=[O:23])=[CH:18][CH:17]=1>C(Cl)Cl>[C:8]([C:3]1([CH2:2][O:1][S:22]([C:19]2[CH:20]=[CH:21][C:16]([CH3:26])=[CH:17][CH:18]=2)(=[O:24])=[O:23])[CH2:7][CH2:6][CH2:5][CH2:4]1)#[N:9]参加物
5
実験手順
At 0° C., to a solution of 1-hydroxymethyl-cyclopentanecarbonitrile (10 g, 79.9 mmol) in CH2Cl2 (100 mL) was added pyridine (6.3 g, 79.9 mmol) and p-toluenesulfonyl chloride (12.18 g, 63.9 mmol). After stirred for 3 h, the solution was concentrated and the residue was used for next step reaction without further purification.
後処理
- concentrationthe solution was concentrated
- customthe residue was used for next step reaction without further purification
出典と根拠
- ORDレコード
- ord-ffe90d2f7028486fb70e6fbb91d77abb
- 出典データセット
- uspto-grants-2010_08
- 特許番号
- US07776875B2
反応ノート
読み込み中…