Diketene → (S)-5-[(3,5-bis-trifluoromethyl-benzyl)-(3-oxo-butyryl)-amino]-7-methyl-8-trifluoromethyl-2,3,4,5-tetrahydro-benzo[b]azepine-1-carboxylic acid tert-butyl ester
反応式
[F:1][C:2]([F:39])([F:38])[C:3]1[CH:4]=[C:5]([CH:31]=[C:32]([C:34]([F:37])([F:36])[F:35])[CH:33]=1)[CH2:6][NH:7][C@H:8]1[CH2:14][CH2:13][CH2:12][N:11]([C:15]([O:17][C:18]([CH3:21])([CH3:20])[CH3:19])=[O:16])[C:10]2[CH:22]=[C:23]([C:27]([F:30])([F:29])[F:28])[C:24]([CH3:26])=[CH:25][C:9]1=2.[CH2:40]=[C:41]1[O:45][C:43](=[O:44])[CH2:42]1>CN(C)C1C=CN=CC=1.O1CCCC1>[C:18]([O:17][C:15]([N:11]1[CH2:12][CH2:13][CH2:14][C@H:8]([N:7]([CH2:6][C:5]2[CH:31]=[C:32]([C:34]([F:35])([F:37])[F:36])[CH:33]=[C:3]([C:2]([F:1])([F:38])[F:39])[CH:4]=2)[C:43](=[O:44])[CH2:42][C:41](=[O:45])[CH3:40])[C:9]2[CH:25]=[C:24]([CH3:26])[C:23]([C:27]([F:30])([F:28])[F:29])=[CH:22][C:10]1=2)=[O:16])([CH3:19])([CH3:21])[CH3:20]参加物
5
