Oxalyl chloride → 2-Chloro-6-methylbenzoyl isocyanate

HRID 508760

反応式

HRID 508760 の反応式
[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]([CH3:11])[C:3]=1[C:4]([NH2:6])=[O:5].C(Cl)(=O)[C:13](Cl)=[O:14]>C(Cl)CCl>[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]([CH3:11])[C:3]=1[C:4]([N:6]=[C:13]=[O:14])=[O:5]

参加物

4

反応物 2

HCID 65578Oxalyl chlorideHCID 113589Benzamide, 2-chloro-6-methyl-

生成物 1

HCID 900195972-Chloro-6-methylbenzoyl isocyanate収率 86.7%

試薬・触媒・溶媒 1

HCID 111,2-Dichloroethane溶媒

実験手順

The title compound was prepared according to the procedure described in step-2 of Intermediate-8 by using 2-chloro-6-methylbenzamide (1.0 g, 5.9 mmol), oxalyl chloride (0.894 g, 7.1 mmol) and EDC (20 mL) to afford 1.00 g of the desired product.

後処理

  1. customThe title compound was prepared

出典と根拠

ORDレコード
ord-6ca60b71c0ef483e81bb004925663dd6
出典データセット
uspto-grants-2015_08
特許番号
US09096545B2

関連ノート

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