Oxalyl chloride → 2-Fluoro-4-(trifluoromethyl)benzoyl isocyanate
反応式
[F:1][C:2]1[CH:10]=[C:9]([C:11]([F:14])([F:13])[F:12])[CH:8]=[CH:7][C:3]=1[C:4]([NH2:6])=[O:5].C(Cl)(=O)[C:16](Cl)=[O:17]>C(Cl)CCl>[F:1][C:2]1[CH:10]=[C:9]([C:11]([F:12])([F:13])[F:14])[CH:8]=[CH:7][C:3]=1[C:4]([N:6]=[C:16]=[O:17])=[O:5]参加物
4
実験手順
The title compound was prepared according to the procedure described in step-2 of Intermediate-8 by using 2-fluoro-4-(trifluoromethyl)benzamide (0.200 g, 0.96 mmol), EDC (10 mL) and oxalyl chloride (0.1 mL, 1.15 mmol) to afford 0.200 g of the product.
出典と根拠
- ORDレコード
- ord-33caabd6fd8a4d2b825ad1a16d0ef143
- 出典データセット
- uspto-grants-2015_08
- 特許番号
- US09096545B2
反応ノート
読み込み中…