反応式
[CH2:1]([NH:8][CH2:9][C:10]([OH:12])=[O:11])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[ClH:13].[CH3:14]O>O1CCOCC1>[ClH:13].[CH2:1]([NH:8][CH2:9][C:10]([O:12][CH3:14])=[O:11])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1参加物
5
実験手順
To a N-benzyl glycine 26 (500 mg, 3.0 mmol) in MeOH (6 mL) was added 4M solution of HCl in dioxane (4 mL) and stirred overnight. The reaction mixture was concentrated to afford compound 27 (649 mg, 99%) as a white solid. The crude compound was carried forward without further purification. LRMS (ESI): (calc) 179.2 (found) 180.1 (MH)+.
後処理
- concentrationThe reaction mixture was concentrated
出典と根拠
- ORDレコード
- ord-38f9f87398bf4542975c2b2409b64c8e
- 出典データセット
- uspto-grants-2015_08
- 特許番号
- US09096565B2
関連ノート
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