(2,3-Dimethoxyphenyl)(4-pyridinyl)methanol → (2,3-Dimethoxyphenyl)(piperidin-4-yl)methanol
反応式
[OH:1][CH:2]([C:13]1[CH:18]=[CH:17][N:16]=[CH:15][CH:14]=1)[C:3]1[CH:8]=[CH:7][CH:6]=[C:5]([O:9][CH3:10])[C:4]=1[O:11][CH3:12]>N1C=CC=CC=1>[OH:1][CH:2]([CH:13]1[CH2:14][CH2:15][NH:16][CH2:17][CH2:18]1)[C:3]1[CH:8]=[CH:7][CH:6]=[C:5]([O:9][CH3:10])[C:4]=1[O:11][CH3:12]参加物
3
実験手順
In Scheme N, step b, the pyridine functionality of 4-[1-hydroxy-1-(2,3-dimethoxyphenyl)methyl]pyridine (10) is reduced to give 4-[1-hydroxy-1-(2,3-dimethoxyphenyl)methyl]piperidine (11) as described previously in Scheme F, step e.
出典と根拠
- ORDレコード
- ord-305ca315bbaa4e218e6ae3bd460c0e67
- 出典データセット
- uspto-grants-2004_03
- 特許番号
- US06713627B2
反応ノート
読み込み中…