Phosphorus oxychloride → HCID 15228889、化合物
反応式
[CH:1]1[CH:6]=[C:5]2[C:7]([C:15]([OH:17])=[O:16])=[C:8]([C:12]([OH:14])=O)[C:9]([NH:11][C:4]2=[CH:3][CH:2]=1)=[O:10].P(Cl)(Cl)(Cl)=O>C(Cl)(Cl)Cl>[C:15]1(=[O:16])[C:7]2[C:5]3[CH:6]=[CH:1][CH:2]=[CH:3][C:4]=3[NH:11][C:9](=[O:10])[C:8]=2[C:12](=[O:14])[O:17]1参加物
4
実験手順
A mixture of 2(1H)-Oxo-quinoline-3,4-dicarboxylic acid (2 g), phosphorous oxychloride (4 g) and dry chloroform (30 mL) was heated at reflux for 2 h. The solvent and excess reagents are removed in vacuo and the residue was treated with ice water to afford Furo[3,4-c]quinoline-1,3,4(5H)-trione as a yellow solid.
後処理
- temperaturewas heated
- temperatureat reflux for 2 h
- customThe solvent and excess reagents are removed in vacuo
- additionthe residue was treated with ice water
出典と根拠
- ORDレコード
- ord-146b31ec172a43eb9907724661a2a7f5
- 出典データセット
- uspto-grants-1993_09
- 特許番号
- US05243049
反応ノート
読み込み中…