m-Aminoacetanilide → 6-(3-Acetamidophenylamino)-4-(thiophen-2-ylmethylamino)nicotinamide

反応式

Cl[C:2]1[CH:10]=[C:9]([NH:11][CH2:12][C:13]2[S:14][CH:15]=[CH:16][CH:17]=2)[C:5]([C:6]([NH2:8])=[O:7])=[CH:4][N:3]=1.[NH2:18][C:19]1[CH:20]=[C:21]([CH:26]=[CH:27][CH:28]=1)[NH:22][C:23](=[O:25])[CH3:24].C1(O[Na])C=CC=CC=1.O.O.O.CC1(C)C2C(=C(P(C3C=CC=CC=3)C3C=CC=CC=3)C=CC=2)OC2C(P(C3C=CC=CC=3)C3C=CC=CC=3)=CC=CC1=2>O1CCOCC1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.[Pd].[Pd]>[C:23]([NH:22][C:21]1[CH:20]=[C:19]([NH:18][C:2]2[CH:10]=[C:9]([NH:11][CH2:12][C:13]3[S:14][CH:15]=[CH:16][CH:17]=3)[C:5]([C:6]([NH2:8])=[O:7])=[CH:4][N:3]=2)[CH:28]=[CH:27][CH:26]=1)(=[O:25])[CH3:24]