Water → p-Nitrotoluene-m-sulfonic acid
反応式
F[C:2]1[CH:7]=[C:6]([CH3:8])[CH:5]=[CH:4][C:3]=1[N+:9]([O-:11])=[O:10].[O-:12][S:13]([O-:15])=[O:14].[Na+].[Na+].O>CCO>[CH3:8][C:6]1[CH:5]=[CH:4][C:3]([N+:9]([O-:11])=[O:10])=[C:2]([S:13]([OH:15])(=[O:14])=[O:12])[CH:7]=1参加物
5
実験手順
In a similar fashion using route 39 general procedure 95, 2-fluoro-4-methyl-1-nitrobenzene (2 g, 12.9 mmol) in EtOH (24 ml) and Na2SO3 (2.04 g, 16.0 mmol) in EtOH:water (40 ml: 32 ml) at 70° C. for 14 h gave the title compound (7 g) which was used in the next step without further purification.
出典と根拠
- ORDレコード
- ord-45c3b4e44c8f4e3ea4ea73ca7dd7cc77
- 出典データセット
- uspto-grants-2015_08
- 特許番号
- US09102688B2
反応ノート
読み込み中…